Sirens

[Wjames]

At eight o’clock a din sounds out,
signifying our need to win. I think that "win" is pretty weak, you could find replace it with something better. Especially at the beginning of a poem, need to draw the reader in.
Car horns and fervent palms
disrupt the sterile calm. Strong choice of word, "sterile".

A discord to drown 
out its fatal silence,
and its blatant disregard "its" in this line and the previous is fairly confusing. What is "it" referring to? The sterile calm? I think replacing the "its" in the previous line with "the", and cutting the "its" in this line might be stronger.
of the rhythms of human life.
Dissonant sirens
ensure that we cannot forget. I don't think you need the period here, especially with even not capitalised below.

even for a moment

A beery domestic scene interrupted. I like beer used as an adjective here.
Dissonant sirens:
fear spreads faster than a virus,
a mind killer slithering
across the dunes of London.  I've never been to London, but London and "dunes" aren't something I'd associate. I get you are trying to portray empty streets (at least I think), but I think something other than Dunes could work better.

The sun never reaches my window,
leaves my bedsheets cold. 
Night transforms
my bed into sticky linen. I like this, sweating, stress, etc.
Latent cause and effect.
So easy to forget. Many short sentences in a row in this stanza, sort of disrupts the reading for me, I think you could combine it into longer, more flowing setences.
Before a siren shoulders
through the quiet 
again 

Thanks for sharing, hopefully some of my thoughts are helpful.